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1

The Quinolones || Chemistry and Mechanism of Action of the Quinolone Antibacterials

Brighty, Katherine E.

Year:

2000

Language:

english

File:

PDF, 634 KB

english, 2000

2

Fluoroquinolone antibacterials: SAR, mechanism of action, resistance, and clinical aspects

Thomas D. Gootz, Katherine E. Brighty

Journal:

Medicinal Research Reviews

Year:

1996

Language:

english

File:

PDF, 3.31 MB

english, 1996

3

Flood resilience: consolidating knowledge between and within critical infrastructure sectors

Pearson, Jonathan, Punzo, G., Mayfield, M., Brighty, G., Parsons, A., Collins, P., Jeavons, S., Tagg, A.

Journal:

Environment Systems and Decisions

Year:

2018

Language:

english

File:

PDF, 1.31 MB

english, 2018

4

Phytochemical composition and antioxidant activity of coconut cotyledon

Nyayiru Kannaian, Udaya Prakash, Edwin, Jasmine Brighty, Rajagopal, Vidhya, Nannu Shankar, Sripriya, Srinivasan, Bhuvaneswari

Journal:

Year:

2020

Language:

english

File:

PDF, 873 KB

english, 2020

5

Identification of Estrogenic Chemicals in STW Effluent. 1. Chemical Fractionation and in Vitro Biological Screening

Desbrow, C., Routledge, E. J., Brighty, G. C., Sumpter, J. P., Waldock, M.

Journal:

Environmental Science & Technology

Year:

1998

Language:

english

File:

PDF, 205 KB

english, 1998

6

Charge-Surrounded Pockets and Electrostatic Interactions with Small Ions Modulate the Activity of Retroviral Fusion Proteins

Lamb, Daniel, Schüttelkopf, Alexander W., van Aalten, Daan M. F., Brighty, David W., Farzan, Michael

Journal:

Year:

2011

Language:

english

File:

PDF, 5.44 MB

english, 2011

7

“Inverse Drug Discovery” Strategy To Identify Proteins That Are Targeted by Latent Electrophiles As Exemplified by Aryl Fluorosulfates

Mortenson, David E., Brighty, Gabriel J., Plate, Lars, Bare, Grant, Chen, Wentao, Li, Suhua, Wang, Hua, Cravatt, Benjamin F., Forli, Stefano, Powers, Evan T., Sharpless, K. Barry, Wilson, Ian A., Kell

Journal:

Journal of the American Chemical Society

Year:

2017

Language:

english

File:

PDF, 4.51 MB

english, 2017

8

Long Terminal Repeat Circular DNA as Markers of Active Viral Replication of Human T Lymphotropic Virus-1 in Vivo

Fox, James, Hilburn, Silva, Demontis, Maria-Antonietta, Brighty, David, Rios Grassi, Maria, Galvão-Castro, Bernardo, Taylor, Graham, Martin, Fabiola

Journal:

Year:

2016

Language:

english

File:

PDF, 977 KB

english, 2016

9

Knowledge and attitudes of family members towards postpartum depression

Poreddi, Vijayalakshmi, Thomas, Beenu, Paulose, Binny, Jose, Binto, Daniel, Brighty M., Somagattu, Sai Nikhil Reddy, B.V., Kathyayani

Journal:

Archives of Psychiatric Nursing

Year:

2020

File:

PDF, 579 KB

2020

10

ChemInform Abstract: Synthesis of (1α,5α,6α)-6-Amino-3-azabicyclo(3.1.0) hexane, a Novel Achiral Diamine.

K. E. BRIGHTY, M. J. CASTALDI

Journal:

Year:

1997

File:

PDF, 34 KB

1997

11

Reduction in the estrogenic activity of a treated sewage effluent discharge to an english river as a result of a decrease in the concentration of industrially derived surfactants

David A. Sheahan, Geoff C. Brighty, Mic Daniel, Susan Jobling, Jule E. Harries, Mark R. Hurst, Joe Kennedy, Sonia J. Kirby, Steven Morris, Edwin J. Routledge, John P. Sumpter, Michael J. Waldock

Journal:

Environmental Toxicology and Chemistry

Year:

2002

Language:

english

File:

PDF, 110 KB

english, 2002

12

Estrogenic activity measured in a sewage treatment works treating industrial inputs containing high concentrations of alkylphenolic compounds—A case study

David A. Sheahan, Geoff C. Brighty, Mic Daniel, Sonia J. Kirby, Mark R. Hurst, Joe Kennedy, Steven Morris, Edwin J. Routledge, John P. Sumpter, Michael J. Waldock

Journal:

Environmental Toxicology and Chemistry

Year:

2002

Language:

english

File:

PDF, 98 KB

english, 2002

13

Synthesis and biological evaluation of novel hygromycin A antibacterial agents

Michael S. Visser, Kevin D. Freeman-Cook, Steven J. Brickner, Katherine E. Brighty, Phuong T. Le, Sarah K. Wade, Rhonda Monahan, Gary J. Martinelli, Kyle T. Blair, Dianna E. Moore

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 1.34 MB

english, 2010

14

The discovery and structure–activity relationships leading to CE-156811, a difluorophenyl cyclopropyl fluoroether: A novel potent antibacterial analog derived from hygromycin A

Phuong T. Le, Steven J. Brickner, Sarah K. Wade, Katherine Brighty, Rhonda Monahan, Gregory G. Stone, Dennis Girard, Steve Finegan, Joan Duignan, John Schafer, Meghan Maloney, Richard P. Zaniewski, An

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2011

Language:

english

File:

PDF, 863 KB

english, 2011

15

Novel fragmentation of 3-lithio-3,6-dihydro-1,2-oxazines: Synthesis of 2,5-dihydro-2-furanylamines

Manoj C. Desai, Jonathan L. Doty, Linda M. Stephens, Katherine E. Brighty

Journal:

Tetrahedron Letters

Year:

1993

Language:

english

File:

PDF, 134 KB

english, 1993

16

Studies on tumor promoters: V. Complementary 1,4-stereocontrol in phorboid cycloheptene synthesis via the divinylcyclopropane rearrangement

Paul A. Wender, Katherine Brighty

Journal:

Tetrahedron Letters

Year:

1988

Language:

english

File:

PDF, 328 KB

english, 1988

17

Robust neutralising activity and activation of neutrophil cytotoxic responses mediated by antibodies targeting the HTLV-1 envelope glycoprotein

Chien-Wen Kuo, Lindsay Tulloch, David W Brighty

Journal:

Year:

2011

Language:

english

File:

PDF, 161 KB

english, 2011

18

Comparative structural analysis of retroviral fusion proteins identifies regions that modulate membrane fusion: a potential retroviral achilles heal?

Daniel Lamb, Alexander W Schüttelkopf, Daan M F van Aalten, David W Brighty

Journal:

Year:

2011

Language:

english

File:

PDF, 161 KB

english, 2011

19

A new phosphine-sulfides-to-phosphine-oxides exchange reaction

Chin H. Chen, Katherine E. Brighty

Journal:

Tetrahedron Letters

Year:

1980

Language:

english

File:

PDF, 243 KB

english, 1980

20

A histological description of intersexuality in the roach

M. Nolan, S. Jobling, G. Brighty, J. P. Sumpter, C. R. Tyler

Journal:

Journal of Fish Biology

Year:

2001

Language:

english

File:

PDF, 8.55 MB

english, 2001

21

ChemInform Abstract: Synthesis of Mono N-Substituted Guanylthioureas.

L. A. REITER, K. E. BRIGHTY, R. A. BRYANT, M. E. GOLDSMITH

Journal:

Year:

1996

File:

PDF, 26 KB

1996

22

ChemInform Abstract: Fluoroquinolone Antibacterials: SAR, Mechanism of Action, Resistance, and Clinical Aspects

T. D. GOOTZ, K. E. BRIGHTY

Journal:

Year:

1996

File:

PDF, 25 KB

1996

23

Soluble recombinant HTLV-1 surface glycoprotein competitively inhibits syncytia formation and viral infection of cells

Sushma R. Jassal, Michael D. Lairmore, Andrew J. Leigh-Brown, David W. Brighty

Journal:

Year:

2001

Language:

english

File:

PDF, 403 KB

english, 2001

24

Synthesis of Mono N-Substituted Guanylthioureas

Reiter, Lawrence A., Brighty, Katherine E., Bryant, Rhonda A., Goldsmith, Miriam E.

Journal:

Synthetic Communications

Year:

1996

Language:

english

File:

PDF, 326 KB

english, 1996

25

In vitro activity of CP-99,219, a novel 7-(3-azabicyclo[3.1.0]hexyl) naphthyridone antimicrobial

Thomas D. Gootz, Katherine E. Brighty, Marge R. Anderson, Brenda J. Schmieder, Suzanne L. Haskell, Joyce A. Sutcliffe, Michael J. Castaldi, Paul R. McGuirk

Journal:

Diagnostic Microbiology and Infectious Disease

Year:

1994

Language:

english

File:

PDF, 708 KB

english, 1994

26

Potential effects of small mammals in high-intensity agricultural systems in east-central Illinois, U.S.A.

Lowell L. Getz, Elaine Brighty

Journal:

Agriculture, Ecosystems & Environment

Year:

1986

Language:

english

File:

PDF, 717 KB

english, 1986

27

Highly specific inhibition of leukaemia virus membrane fusion by interaction of peptide antagonists with a conserved region of the coiled coil of envelope

Daniel Lamb, Alexander W Schüttelkopf, Daan MF van Aalten, David W Brighty

Journal:

Year:

2008

Language:

english

File:

PDF, 1.81 MB

english, 2008

28

Viral interference with host mRNA surveillance, the nonsense-mediated mRNA decay (NMD) pathway, through a new function of HTLV-1 Rex: implications for retroviral replication

Nakano, Kazumi, Ando, Tomomi, Yamagishi, Makoto, Yokoyama, Koichi, Ishida, Takaomi, Ohsugi, Takeo, Tanaka, Yuetsu, Brighty, David W., Watanabe, Toshiki

Journal:

Microbes and Infection

Year:

2013

Language:

english

File:

PDF, 2.15 MB

english, 2013

29

Widespread Sexual Disruption in Wild Fish

Jobling, Susan, Nolan, Monique, Tyler, Charles R., Brighty, Geoff, Sumpter, John P.

Journal:

Environmental Science & Technology

Year:

1998

Language:

english

File:

PDF, 174 KB

english, 1998

30

An Asymmetric Synthesis of (2 S ,5 S )-5-Substituted Azepane-2-Carboxylate Derivatives

Wishka, Donn G., Bédard, Marion, Brighty, Katherine E., Buzon, Richard A., Farley, Kathleen A., Fichtner, Michael W., Kauffman, Goss S., Kooistra, Jaap, Lewis, Jason G., O’Dowd, Hardwin, Samardjiev,

Journal:

Journal of Organic Chemistry

Year:

2011

Language:

english

File:

PDF, 799 KB

english, 2011

31

Relative Potencies and Combination Effects of Steroidal Estrogens in Fish

Thorpe, Karen L., Cummings, Rob I., Hutchinson, Thomas H., Scholze, Martin, Brighty, Geoff, Sumpter, John P., Tyler, Charles R.

Journal:

Environmental Science & Technology

Year:

2003

Language:

english

File:

PDF, 115 KB

english, 2003

32

Probing the Fusion-Active Structures of Envelope of Human T-cell Leukaemia Virus Type-1 with Conformation-Specific Monoclonal Antibodies

Antonis Mirsaliotis, Kulpash Nurkiyanova, C Sharon Kuo, David W Brighty

Journal:

Year:

2005

Language:

english

File:

PDF, 69 KB

english, 2005

33

Probing Cell-to-cell Transfer of Human T-cell Leukaemia Virus Type-1 Using Novel Inhibitors of Viral Entry

C Sharon Kuo, Antonis Mirsaliotis, Kulpash Nurkiyanova, David W Brighty

Journal:

Year:

2005

Language:

english

File:

PDF, 69 KB

english, 2005

34

Epitopes recognised by neutralising and non-neutralising anti-envelope antibodies define surface exposed regions of HTLV-1 envelope

Brighty, David W, Arainga, Mariluz, Kuo, Chien-Wen S, Fernades, Abigail

Journal:

Year:

2014

Language:

english

File:

PDF, 71 KB

english, 2014

35

Staff Education in Public Health Nursing

KATE S. BRIGHTY

Journal:

Canadian Public Health Journal

Year:

1937

Language:

english

File:

PDF, 327 KB

english, 1937

36

Public Health Nursing: Modern Trends in Public Health Nursing

Ruby M. Simpson, George Hanna and Kate Shaw Brighty

Journal:

Canadian Public Health Journal

Year:

1932

Language:

english

File:

PDF, 349 KB

english, 1932

37

Exposure of Juvenile Roach ( Rutilus rutilus ) to Treated Sewage Effluent Induces Dose-Dependent and Persistent Disruption in Gonadal Duct Development

Rodgers-Gray, Trevor P., Jobling, Susan, Kelly, Carole, Morris, Steven, Brighty, Geoff, Waldock, Michael J., Sumpter, John P., Tyler, Charles R.

Journal:

Environmental Science & Technology

Year:

2001

Language:

english

File:

PDF, 394 KB

english, 2001

38

Estimating the Effects of 17α-Ethinylestradiol on Populations of the Fathead Minnow Pimephales promelas : Are Conventional Toxicological Endpoints Adequate?

Grist, Eric P. M., Wells, N. Claire, Whitehouse, Paul, Brighty, Geoff, Crane, Mark

Journal:

Environmental Science & Technology

Year:

2003

Language:

english

File:

PDF, 143 KB

english, 2003

39

Divergent Modulation of Src-Family Kinase Regulatory Interactions with ATP-Competitive Inhibitors

Leonard, Stephen E., Register, A. C., Krishnamurty, Ratika, Brighty, Gabriel J., Maly, Dustin J.

Journal:

ACS Chemical Biology

Year:

2014

Language:

english

File:

PDF, 3.18 MB

english, 2014

40

Synthesis of phosphalilolidine and phosphajulolidine

Chen, Chin H., Brighty, Katherine E., Michaels, Frank M.

Journal:

Journal of Organic Chemistry

Year:

1981

Language:

english

File:

PDF, 945 KB

english, 1981

41

Identification of Estrogenic Chemicals in STW Effluent. 2. In Vivo Responses in Trout and Roach

Routledge, E. J., Sheahan, D., Desbrow, C., Brighty, G. C., Waldock, M., Sumpter, J. P.

Journal:

Environmental Science & Technology

Year:

1998

Language:

english

File:

PDF, 182 KB

english, 1998

42

The chemistry and biological profile of trovafloxacin

Brighty, K. E., Gootz, T. D.

Journal:

Journal of Antimicrobial Chemotherapy

Year:

1997

Language:

english

File:

PDF, 188 KB

english, 1997

43

Basic Residues Are Critical to the Activity of Peptide Inhibitors of Human T Cell Leukemia Virus Type 1 Entry

Lamb, D., Mirsaliotis, A., Kelly, S. M., Brighty, D. W.

Journal:

Journal of Biological Chemistry

Year:

2009

Language:

english

File:

PDF, 1.09 MB

english, 2009

44

Resistance to Neutralization by Antibodies Targeting the Coiled Coil of Fusion-active Envelope Is a Common Feature of Retroviruses

Mirsaliotis, A., Nurkiyanova, K., Lamb, D., Kuo, C.-W. S., Brighty, D. W.

Journal:

Journal of Biological Chemistry

Year:

2007

Language:

english

File:

PDF, 1.19 MB

english, 2007

45

A Leptomycin B-sensitive Homologue of Human CRM1 Promotes Nuclear Export of Nuclear Export Sequence-containing Proteins inDrosophila Cells

Fasken, M. B., Saunders, R., Rosenberg, M., Brighty, D. W.

Journal:

Journal of Biological Chemistry

Year:

2000

Language:

english

File:

PDF, 1.00 MB

english, 2000

46

Antibodies to the Envelope Glycoprotein of Human T Cell Leukemia Virus Type 1 Robustly Activate Cell-Mediated Cytotoxic Responses and Directly Neutralize Viral Infectivity at Multiple Steps of the Entry Process

Kuo, C.-W. S., Mirsaliotis, A., Brighty, D. W.

Journal:

The Journal of Immunology

Year:

2011

Language:

english

File:

PDF, 1.09 MB

english, 2011

47

Human T-Cell Leukemia Virus Type 1 Envelope Glycoprotein gp46 Interacts with Cell Surface Heparan Sulfate Proteoglycans

Pinon, J. D., Klasse, P. J., Jassal, S. R., Welson, S., Weber, J., Brighty, D. W., Sattentau, Q. J.

Journal:

Journal of Virology

Year:

2003

Language:

english

File:

PDF, 748 KB

english, 2003

48

Conformation-Specific Antibodies Targeting the Trimer-of-Hairpins Motif of the Human T-Cell Leukemia Virus Type 1 Transmembrane Glycoprotein Recognize the Viral Envelope but Fail To Neutralize Viral Entry

Mirsaliotis, A., Nurkiyanova, K., Lamb, D., Woof, J. M., Brighty, D. W.

Journal:

Journal of Virology

Year:

2007

Language:

english

File:

PDF, 656 KB

english, 2007

49

Human T-Cell Leukemia Virus Type 1 Receptor Expression among Syncytium-Resistant Cell Lines Revealed by a Novel Surface Glycoprotein-Immunoadhesin

Jassal, S. R., Pohler, R. G., Brighty, D. W.

Journal:

Journal of Virology

Year:

2001

Language:

english

File:

PDF, 707 KB

english, 2001

50

Predicted Exposures to Steroid Estrogens in U.K. Rivers Correlate with Widespread Sexual Disruption in Wild Fish Populations

Jobling, Susan, Williams, Richard, Johnson, Andrew, Taylor, Ayesha, Gross-Sorokin, Melanie, Nolan, Monique, Tyler, Charles R., van Aerle, Ronny, Santos, Eduarda, Brighty, Geoff

Journal:

Environmental Health Perspectives

Year:

2005

Language:

english

File:

PDF, 173 KB

english, 2005